BSDB: the biomolecule stretching database

نویسندگان

  • Mateusz Sikora
  • Joanna I. Sulkowska
  • Bartlomiej S. Witkowski
  • Marek Cieplak
چکیده

We describe the Biomolecule Stretching Data Base that has been recently set up at http://www.ifpan.edu.pl/BSDB/. It provides information about mechanostability of proteins. Its core is based on simulations of stretching of 17 134 proteins within a structure-based model. The primary information is about the heights of the maximal force peaks, the force-displacement patterns, and the sequencing of the contact-rupturing events. We also summarize the possible types of the mechanical clamps, i.e. the motifs which are responsible for a protein's resistance to stretching.

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عنوان ژورنال:

دوره 39  شماره 

صفحات  -

تاریخ انتشار 2011